Day One |
1 November |
10.00 |
Welcome and Introduction Steve Smye (University of Leeds) and Matt Kaiser (Cancer Research UK) |
Session 1 |
Clinical challenges: understanding how and where cancer spreads, chaired by Steve Smye (University of Leeds) |
10.10 |
Keynote: Setting the grand challenge Kairbaan Hodivala-Dilke (Cancer Research UK Barts Centre & QMUL) 'What governs metastasis: where, when and who' |
10.40 |
Samra Turajilic (Francis Crick Institute) 'Insights into metastatic competence from human studies' |
11.00 |
Harriet Wikman (Institute of Tumour Biology, Hamburg) 'Using liquid biopsies to understand metastasis' |
11.20 |
Roberto Vendramin (UCL) 'Cancer Evolution: Darwin and Beyond’ |
11.40 |
Panel Q&A |
12.10 |
Lunch with option to network on the Wonder platform (links provided within the meeting) |
13.10 |
Keynote: Robert Gatenby (Moffitt Cancer Center, USA) 'Harnessing evolutionary dynamics to control and cure metastatic cancers' |
13.40 |
Q and A |
Session 2 |
Impact of cellular shape, Chaired by Kairbaan Hodivala-Dilke (Cancer Research UK Barts Centre & QMUL) |
13.50 |
Helen Matthews (University of Sheffield) ‘The control of cell shape and mechanics during cancer cell division’ |
14.10 |
Jody Rosenblatt (KCL) 'The role of mechanical cell extrusion in maintaining equilibrium in the epithelium' |
14.30 |
Vicky Sanz-Moreno (QMUL) 'The actomyosin cytoskeleton as a therapeutic target in cancer' |
14.50 |
Panel Q&A |
15.30 |
End of Day one |
Day Two |
2 November |
Session 3 |
Migration, Chaired by Jamie Hobbs (University of Sheffield) |
9.30 |
Julia Yeomans (Oxford University) 'The dynamics of collective cell motility' |
9.50 |
Caterina La Porta (University of Milan) 'Phase transitions in cell migration' |
10.10 |
Robert Insall (Glasgow University) 'Why do cancer cells spread? A multidisciplinary approach to chemotactic information' |
10.30 |
Refreshment Break |
10.50 |
Ilaria Malanchi (Francis Crick Institute) 'The organised chaos of the metastatic environment' |
11.10 |
Patrick Caswell (Manchester) 'Matrix assembly in the ovarian cancer metastatic niche' |
11.30 |
Panel Q&A |
12.00 |
Lunch with option to network on the Wonder platform (links provided within the meeting) |
Session 4 |
Modelling, Chaired by Robert Insall (Glasgow University) |
13.00 |
Mihaela Lorger, (Leeds) 'Pre-clinical models of brain metastases; what do they tell us?' |
13.20 |
Trevor Graham (Cancer Research UK Barts Centre & QMUL) 'Mathematical modelling to understand the role of clonal selection in metastasis' |
13.40 |
Víctor M. Pérez García (University of Castilla-La Mancha, Spain) 'What can we learn about metastasis from allometric scaling laws?' |
14.00 |
Refreshment Break |
14.10 |
Erik Sahai (Francis Crick Institute) 'Models to predict treatment failure /progression/ metastasis formation' |
14.30 |
Michael Hinczewski (Case Western Reserve University, USA) 'Enhancing adaptive therapies by using techniques from quantum physics' |
14.50 |
Panel Q&A |
15.20 |
Open and Emerging Questions from the workshop What are the “big questions”? |
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