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  • Home
  • About
    • Meet the team
    • Our network
    • IoP Rosalind Franklin Medal
    • PoL SPF link
    • EDI policy
    • Privacy Notice
  • PoLNET3
    • Steering Group
    • Physics of Life Roadmap
    • Funding Opportunities >
      • EDI award
      • PoLNET PDRA Call 2023
    • Early Career Researchers
    • Events >
      • PoLNET3 Past Events >
        • Physics of Life 2025
        • Physics of Life PDRA Recipient Event
        • BBS Biennial Meeting 2024
        • Biofilaments Workshop 2024
        • Winter School: challenges and opportunities in Physics of Life
        • Non-equilibrium explorations on the physics of life : remembering the biological physics of Tom McLeish
        • NOTICE - Novel Optical Technology in Cardiac Electrophysiology
        • Physics of Life Summer School 2022
        • Motility in Microbes, Molecules and Matter 2
        • Tissue dynamics
        • Physics of Life: ECR bootcamp
        • Physics of Life 2023
        • Cutting-edge methods for bacterial pathogen interactions with host cells
        • Motility in Microbes, Molecules and Matter
        • Periodic patterns
        • Physics of Life ECR workshop
        • Physics of Life/iPoLS seminar
        • Biophysics and evolution
        • Launch
  • Physics of Medicine
    • Steering Group
    • Physics of Medicine Events >
      • Past Events >
        • Translational Ageing
        • Tackling drug resistance in cancer
        • Inflammatory Bowel Disease
        • Physics of Viruses
        • Antimicrobial Resistance
        • Metastasis Workshop
        • Neurodegenerative disease
        • Physics of Brains
  • POLNET 2
    • PoLNET2 team
    • Student Summer Bursaries 2019
    • Events >
      • PoLNET2 Past Events >
        • Sandpits
        • Past summer schools >
          • Summer School: Physics of Life Summer School: From Cells to Tissues and Organisms
          • Summer School: New approaches to Biomolecular function, structure and dynamics
        • Physics of Life Town Meetings >
          • Town Meeting 2019
          • Town Meeting 2018
          • Town Meeting 2017
        • Past Workshops >
          • QMGR V
          • Non-equilibrium Cold Plasmas in Biology and Medicine
          • The Fundamentals of Late Stage Cancer
          • The Physics of Evolution
          • Nanostructures at Soft Interfaces: Technology and Biophysics
          • Physics of Biological Oscillators
          • The Future of Optical Techniques in Biology
          • Tom McLeish's Durham farewell symposium
          • Multiscale mechanics in Biology
          • Epigenetics
          • Physics of Animal Health
          • Interdisciplinary Challenges in Non-Equilibrium Physics
          • Cancer Workshop
          • QMGR
          • Symmetry
          • Nanofluidics
          • Quantum Biology
          • Antimicrobial Resistance
          • Filaments and Cellular Responses
          • Biocomputation
          • Workshop Reports
  • PoLNET 1
    • PoLNET 1 Team
    • PoLNET1 Past Events >
      • Launch meeting 2013
      • Plenary Event 1: The Living Cell
      • Plenary Event 2: Synthetic Biology
      • Plenary Event 3: Multicellularity
      • Focussed Workshops >
        • 1: The Physics of Bacterial Infection
        • 2: Forces in Biology
        • 3: Life in Extreme Environments
        • 4: The Physics of Cancer
        • 5: Information Flow in Biological Systems
        • 6: Pattern Formation and Morphogenesis
        • 7: Compartmentalisation & Confinement
        • 8: Physics of Bacterial Biofilms
        • 9: Cancer Sandpit
      • Summer/Winter schools >
        • Summer School
        • Winter School
      • Final Summit
    • Roadmap for Biological Physics
  • Useful Links
  • Contact us

Rosetrees Interdisciplinary workshop: Metastasis

1 and 2 November 2021
Online, Via Zoom webinar
In collaboration with:
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Image courtesy of Jorge Almagro, Adult Stem Cell Laboratory, Francis Crick Institute.

Workshop Overview

The contribution of physics and biology to understanding cancer is long-standing and increasingly well-recognised. Recent major strategic initiatives, including the National Institutes of Health “Physical Sciences in Oncology”, and Cancer Research UK Multidisciplinary award scheme, reflect this increasing recognition and are intended to strengthen collaboration between the physical sciences and biological research communities in order to better address the “Grand Challenges” in cancer research.
​

This  workshop, funded by the Rosetrees Trust through the Physics of Medicine network, will bring together clinicians, biologists and physicists to show-case successful existing collaborations and promote engagement, new ideas and collaborations aimed at addressing one important aspect of cancer, metastasis.

Who should attend?

We invite participation by academic, industrial and clinical research scientists who are interested in the central goal of generating new collaborative research interactions at the physical/life sciences interface focused on this subject area. 

Programme

Please note, all times are in UK time (GMT)
Day One
1 November
10.00
Welcome and Introduction
​
Steve Smye (University of Leeds) and Matt Kaiser (Cancer Research UK)
Session 1
Clinical challenges: understanding how and where cancer spreads, chaired by Steve Smye (University of Leeds)
10.10
Keynote: Setting the grand challenge
Kairbaan Hodivala-Dilke (Cancer Research UK Barts Centre & QMUL) 'What governs metastasis: where, when and who'   ​
10.40
Samra Turajilic (Francis Crick Institute) 'Insights into metastatic competence from human studies'
11.00
Harriet Wikman (Institute of Tumour Biology, Hamburg) 'Using liquid biopsies to understand metastasis'
11.20
Roberto Vendramin (UCL) 'Cancer Evolution: Darwin and Beyond’ 
11.40
Panel Q&A
12.10
Lunch with option to network on the Wonder platform (links provided within the meeting) 
13.10
Keynote:
Robert Gatenby (Moffitt Cancer Center, USA) 'Harnessing evolutionary dynamics to control and cure metastatic cancers'
13.40
Q and A
Session 2
​Impact of cellular shape, Chaired by Kairbaan Hodivala-Dilke (Cancer Research UK Barts Centre & QMUL)
13.50
Helen Matthews (University of Sheffield) ‘The control of cell shape and mechanics during cancer cell division’
​14.10
Jody Rosenblatt (KCL) 'The role of mechanical cell extrusion in maintaining equilibrium in the epithelium'
​14.30
​Vicky Sanz-Moreno (QMUL)  'The actomyosin cytoskeleton as a therapeutic target in cancer'​
​14.50
Panel Q&A
15.30
End of Day one
Day Two
2 November​​
​Session 3
​​Migration, Chaired by Jamie Hobbs (University of Sheffield)
9.30
Julia Yeomans (Oxford University) 'The dynamics of collective cell motility'
9.50
​Caterina La Porta (University of Milan) 'Phase transitions in cell migration'
10.10
​Robert Insall (Glasgow University) 'Why do cancer cells spread? A multidisciplinary approach to chemotactic information'
​10.30
​Refreshment Break
10.50
Ilaria Malanchi (Francis Crick Institute) 'The organised chaos of the metastatic environment'
​11.10
Patrick Caswell (Manchester) 'Matrix assembly in the ovarian cancer metastatic niche​'
11.30
Panel Q&A​
12.00
Lunch with option to network on the Wonder platform (links provided within the meeting) ​
Session 4
Modelling, Chaired by Robert Insall (Glasgow University) ​
13.00
Mihaela Lorger, (Leeds) 'Pre-clinical models of brain metastases; what do they tell us?'
13.20
Trevor Graham (Cancer Research UK Barts Centre & QMUL) 'Mathematical modelling to understand the role of clonal selection in metastasis'
13.40
Víctor M. Pérez García (University of Castilla-La Mancha, Spain) 'What can we learn about metastasis from allometric scaling laws?'
14.00
Refreshment Break
14.10
Erik Sahai (Francis Crick Institute) 'Models to predict treatment failure /progression/ metastasis formation'
​14.30
Michael Hinczewski  (Case Western Reserve University, USA) 'Enhancing adaptive therapies by using techniques from quantum physics'
14.50
Panel Q&A
15.20
​Open and Emerging Questions from the workshop What are the “big questions”?

Workshop Publication

Interdisciplinary approaches to metastasis - https://www.cell.com/iscience/fulltext/S2589-0042(22)01287-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004222012871%3Fshowall%3Dtrue

Workshop Recordings

Funded by:                                                                                                 Managed bY:

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